Ion channels are fascinating structures composed of amino acids embedded within cell membranes. Among other functions, ion channels act as intracellular messengers and make muscle contractions … more
We’re big movie fans in our house and we love to see how our favorites were made. While exploring the “behind-the-scenes” featurettes on our copy of Disney•Pixar’s Brave I … more
Video Url: http://c450255.r55.cf2.rackcdn.com/encode.mp4
Dr. Fuz Rana reports on phase 2 of the Encode project, biochemical research that he calls the most important of his lifetime.
UPDATE June 2013: This updated version of Dr. Rana's talk includes … more
For several decades, biochemists thought a vast proportion of most organisms’ genomes consisted of junk—DNA sequences that once had value but decayed into nonfunctional elements as a … more
Episode #240: Design of Antifreeze Proteins more
They prey on their own kind. Some might call it cannibalism, but it’s the only way they can survive. Indeed, the zombie apocalypse is here.
So-called “zombies” exist … more
A few days ago I wrote about the ENCODE project and the new recognition that, at minimum, 80 percent of the human genome consists of functional DNA elements. Despite some skeptics’ complaints … more
“I think that the formulation of [DNA’s] structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years.” … more
A few days ago I wrote about a recent advance in biotechnology that highlights the incredible information-carrying capacity of DNA. This biomolecule can store information, because it is an … more
“When I get a little money I buy books; if any is left I buy food and clothes.”
I love books. As soon as you walk into our house, you will see that this is true. … more
RTB’s Fuz Rana calls it the biggest discovery of his lifetime as a biochemist.
A massive new DNA research project called ENCODE has dramatically increased understanding of the human genome and … more
A few days ago I wrote about the molecular rotary motor F1-F0-ATPase, arguing that its supramolecular architecture and operation bear an uncanny similarity to a man-made machine. This similarity … more
I don’t like to be criticized—not. one. bit. But if I am honest with myself, there is almost always some measure of validity to the critical comments directed my way.
As my friend, who is … more
A few days ago, I described new work that demonstrates the optimal design of the cell’s metabolism. Many other features of the cell’s chemistry are optimized as well. In fact, optimality … more
One of the biggest shocks I experienced when we moved from Cincinnati to the Los Angeles area thirteen years ago was the traffic—and the complexity of the Southern California freeway … more
In a few days, fervent fans will scatter to the nearest theater to catch one of the most anticipated movies of the summer: The Amazing Spider-Man.
An exciting little detail about this franchise … more
Cite Omer Barad et al, “Efficiency and Specificity in microRNA Biogenesis,” Nature Structural and Molecular Biology 19 (2012): 650-652 more
Editors aren’t Borgs. Honest. But we often stress that resistance to saving multiple versions of the same document is futile. This practice might seem redundant and unnecessary, but when an … more
Cecile Leduc et al., “Molecular Crowding Creates Traffic Jams of Kinesis Motors on Microtubules,” Proceedings of the National Academy of Sciences 109 (2012): 6100-6105. more
Who’s the father of computer science? Although not a household name, Alan Turing (1912–1954) and his work have impacted nearly every facet of human existence. When he was 24 years of age, … more