Reasons to Believe

Biochemical Design

  • Do ENCODE Skeptics Protest Too Much? Part 3 (of 3)

    I protest. I take these wise men, that crow so at these set kind of fools, no better than the fools’ zanies.MalvolioTwelfth Night, Act I, scene v****

    When the ENCODE Project announced in … more

  • Do ENCODE Skeptics Protest Too Much? Part 2 (of 3)

    The Lady doth protest too much, methinks.Queen GertrudeHamlet, Act III, scene ii

    Today when someone "protests too much," it can create a suspicion that the protested viewpoint or opinion may actually … more

  • Do ENCODE Skeptics Protest Too Much? Part 1 (of 3)

    The Lady doth protest too much, methinks.Queen GertrudeHamlet, Act III, scene ii

    I love Shakespeare, particularly the tragedies. Many of these stories center on a specific character flaw and explore … more

  • Pixels and Nucleotides: Artistry in the Details

    We’re big movie fans in our house and we love to see how our favorites were made. While exploring the “behind-the-scenes” featurettes on our copy of Disney•Pixar’s Brave I … more

  • ENCODED By Design

    Video Url:

    Dr. Fuz Rana reports on phase 2 of the Encode project, biochemical research that he calls the most important of his lifetime.

    UPDATE June 2013: This updated version of Dr. Rana's talk includes … more

  • ENCODE Junks Evolutionary Concept

    For several decades, biochemists thought a vast proportion of most organisms’ genomes consisted of junk—DNA sequences that once had value but decayed into nonfunctional elements as a … more

  • Eat This: Zombies Are Real

    They prey on their own kind. Some might call it cannibalism, but it’s the only way they can survive. Indeed, the zombie apocalypse is here.

    Sort of.

    So-called “zombies” exist … more

  • Responding to ENCODE “Skeptics”

    “I think that the formulation of [DNA’s] structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years.” … more

  • TNRTB Classic: A Watchmaker’s Design

    A few days ago I wrote about the molecular rotary motor F1-F0-ATPase, arguing that its supramolecular architecture and operation bear an uncanny similarity to a man-made machine. This similarity … more

  • TNRTB Classic: Optimal Design by a Creator

    A few days ago, I described new work that demonstrates the optimal design of the cell’s metabolism. Many other features of the cell’s chemistry are optimized as well. In fact, optimality … more

  • The Optimal Design of Metabolism


    One of the biggest shocks I experienced when we moved from Cincinnati to the Los Angeles area thirteen years ago was the traffic—and the complexity of the Southern California freeway … more

  • Spider-Man Spins a Design Argument

    In a few days, fervent fans will scatter to the nearest theater to catch one of the most anticipated movies of the summer: The Amazing Spider-Man.

    An exciting little detail about this franchise … more